Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | CCKBR | P32239 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14186762 | 0.94 | KDM4E (0.52) | PTPN1CCKBRKDM4EHPGDHSD17B10 | |
| SCHEMBL14177510 | 0.82 | CCKBR (0.61) | PTPN1CCKBRMMP9MMP8CCKAR | |
| SCHEMBL20622707 | 0.82 | KDM4E (0.57) | KDM4EHPGDHSD17B10MMP9MMP8 | |
| SCHEMBL8242416 | 0.82 | KDM4E (0.57) | KDM4EHPGDHSD17B10MMP9MMP8 | |
| SCHEMBL8360548 | 0.80 | CCKBR (0.65) | PTPN1CCKBRCCKAR | |
| SCHEMBL8241583 | 0.80 | PTPN1 (0.58) | PTPN1HSD17B10MEN1KMT2A | |
| SCHEMBL8363913 | 0.78 | PTPN1 (0.65) | PTPN1CCKBRMMP9MMP8PSMB5 | |
| SCHEMBL8242399 | 0.78 | KDM4E (0.55) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL8363911 | 0.78 | ICMT (0.52) | MMP9MMP8CNR1CNR2ICMT | |
| SCHEMBL8241488 | 0.78 | ICMT (0.52) | CCKBRCNR1CNR2OPRD1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | CUBIST PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | VIP, DNPEP, PREP | PTPN1 3638/4885CCKBR 2050/4885KDM4E 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.