Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530528 | 0.88 | HRH3 (0.41) | HRH3TLR8TLR7TLR9DRD4 | |
| SCHEMBL8238217 | 0.88 | HRH3 (0.38) | HRH3 | |
| SCHEMBL5529449 | 0.86 | SOS1 (0.41) | HRH3TLR8TLR7TLR9DRD4 | |
| SCHEMBL8236599 | 0.86 | POLB (0.38) | TLR8TLR7TLR9DRD4DRD2 | |
| SCHEMBL8235976 | 0.85 | OPRK1 (0.40) | HRH3TLR8TLR7TLR9DRD2 | |
| SCHEMBL8236219 | 0.83 | HRH3 (0.41) | HRH3TLR8TLR7TLR9DRD4 | |
| SCHEMBL8231334 | 0.83 | MAPK14 (0.35) | DRD4DRD2MEN1KMT2ASCN1A | |
| SCHEMBL8236186 | 0.83 | SCN8A (0.46) | SCN1ASCN8A | |
| SCHEMBL8238215 | 0.83 | HRH3 (0.39) | HRH3 | |
| SCHEMBL8238556 | 0.83 | OPRK1 (0.37) | TLR8TLR7TLR9ADORA2ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |