Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 4/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8231334 | 0.88 | MAPK14 (0.35) | SCN1ASCN8AMCHR1PDE4BMEN1 | |
| SCHEMBL5530548 | 0.88 | SCN1A (0.39) | POLBL3MBTL1TLR9TLR8TLR7 | |
| SCHEMBL5532059 | 0.87 | SCN1A (0.39) | POLBL3MBTL1SCN1ASCN8A | |
| SCHEMBL8236222 | 0.86 | HRH3 (0.39) | TLR9TLR8TLR7SCN1ASCN8A | |
| SCHEMBL8235976 | 0.85 | OPRK1 (0.40) | TLR9TLR8TLR7PARP1DRD2 | |
| SCHEMBL8238856 | 0.83 | AR (0.38) | POLBL3MBTL1 | |
| SCHEMBL8238217 | 0.83 | HRH3 (0.38) | — | |
| SCHEMBL8238215 | 0.83 | HRH3 (0.39) | — | |
| SCHEMBL8238556 | 0.83 | OPRK1 (0.37) | TLR9TLR8TLR7SCN1ASCN8A | |
| SCHEMBL8236186 | 0.79 | SCN8A (0.46) | SCN1ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |