Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66545 | 0.89 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1GPR183MAPTKDM4E | |
| SCHEMBL90762 | 0.87 | GPR183 (0.52) | ALDH1A1L3MBTL1GPR183RAB9AKMT2A | |
| SCHEMBL65663 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL56480 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1L3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL56987 | 0.76 | KMT2A (0.51) | ALDH1A1L3MBTL1GPR183KMT2AMEN1 | |
| SCHEMBL8243869 | 0.71 | SMN1; SMN2 (0.43) | ALDH1A1L3MBTL1MAPTRAB9AKMT2A | |
| SCHEMBL57050 | 0.70 | KMT2A (0.47) | ALDH1A1L3MBTL1GPR183MAPTRAB9A | |
| SCHEMBL66082 | 0.70 | ENPP2 (0.41) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL65760 | 0.70 | SMN1; SMN2 (0.50) | ALDH1A1L3MBTL1MAPTKDM4ERAB9A | |
| SCHEMBL20989269 | 0.69 | RAB9A (0.62) | ALDH1A1L3MBTL1GPR183MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050522-A1 | DERIVATIVES FOR MODULATION OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-05-03 | — | — | WO | disclosed |