Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 3/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29434720 | 0.71 | ALDH1A1 (0.48) | PARP1CHEK1PIM1RPS6KA3ALDH1A1 | |
| SCHEMBL9898895 | 0.71 | KDM4E (0.47) | PARP1ALDH1A1SMN1; SMN2TNKS2IP6K1 | |
| SCHEMBL3125699 | 0.68 | FABP6 (0.47) | ALDH1A1PNP | |
| SCHEMBL26349442 | 0.68 | PNP (0.50) | PARP1CHEK1PIM1RPS6KA3ALDH1A1 | |
| SCHEMBL10121482 | 0.67 | PARP1 (0.62) | PARP1CHEK1PIM1RPS6KA3ALDH1A1 | |
| SCHEMBL8906319 | 0.67 | ALDH1A1 (0.59) | ALDH1A1PNPPDPK1 | |
| SCHEMBL2749365 | 0.66 | CCNB2 (0.51) | PARP1ALDH1A1PNPPDPK1CA12 | |
| SCHEMBL1415174 | 0.65 | ALDH1A1 (0.52) | PARP1CHEK1PIM1RPS6KA3ALDH1A1 | |
| SCHEMBL11097776 | 0.65 | PARP1 (0.35) | PARP1CHEK1PIM1RPS6KA3ALDH1A1 | |
| SCHEMBL13663973 | 0.65 | PNP (0.62) | PARP1CHEK1PIM1RPS6KA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071738-A1 | CONDENSED HETEROCYCLIC COMPOUNDS USEFUL AS DPP-IV INHIBITORS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |