Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271825 | 0.95 | KDM4E (0.43) | ALDH1A1MAPTS1PR1S1PR3LMNA | |
| SCHEMBL4270743 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBALDH1A1MAPTMEN1 | |
| SCHEMBL4280633 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBALDH1A1MAPTMEN1 | |
| SCHEMBL4277709 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2POLBALDH1A1MAPTMEN1 | |
| SCHEMBL13701424 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBMAPTMEN1KMT2A | |
| SCHEMBL4275365 | 0.90 | KDM4E (0.44) | SMN1; SMN2POLBALDH1A1MAPTLMNA | |
| SCHEMBL13701431 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2POLBALDH1A1MAPTMEN1 | |
| SCHEMBL4281082 | 0.89 | MAPT (0.43) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4271880 | 0.89 | TSHR (0.41) | SMN1; SMN2POLBALDH1A1MAPTMEN1 | |
| SCHEMBL4271315 | 0.88 | FPR2 (0.40) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |