Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163880 | 0.94 | GRM2 (0.45) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL4139579 | 0.86 | CYP2D6 (0.43) | GRM2DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL4151843 | 0.83 | DRD2 (0.46) | GRM2DRD2DRD4DRD3ACHE | |
| SCHEMBL4157977 | 0.81 | GRM2 (0.61) | GRM2DRD2DRD4DRD3 | |
| SCHEMBL4147399 | 0.80 | MAOB (0.46) | GRM2DRD2DRD4DRD3ACHE | |
| SCHEMBL4154130 | 0.76 | MAOB (0.43) | CYP2D6 | |
| SCHEMBL4941482 | 0.75 | LIPG (0.36) | GRM2DRD2DRD4DRD3ACHE | |
| SCHEMBL4142025 | 0.75 | MAOB (0.42) | GRM2DRD2DRD4DRD3CYP2D6 | |
| SCHEMBL4146888 | 0.74 | NPY1R (0.41) | GRM2DRD2DRD3NPY1R | |
| SCHEMBL4161960 | 0.72 | ACHE (0.47) | GRM2DRD2DRD4DRD3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115077-A2 | BICYCLIC BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |