Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557085 | 0.98 | DNM1 (0.46) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11551363 | 0.98 | DNM1 (0.46) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11552759 | 0.98 | DNM1 (0.46) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL20393388 | 0.98 | DNM1 (0.46) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL11138246 | 0.98 | DNM1 (0.46) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL4539635 | 0.94 | DNM1 (0.39) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL28667085 | 0.92 | DNM1 (0.50) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1961496 | 0.91 | RELA (0.46) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL6888361 | 0.88 | ADH1B (0.47) | OPRM1ADH1BADH1CADH1AADH4 | |
| SCHEMBL996511 | 0.88 | DNM1 (0.42) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079130-A2 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2007-07-12 | — | — | WO | disclosed |