Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238174 | 0.89 | RAB9A (0.48) | ALDH1A1LMNANPSR1HSD17B10HSP90AA1 | |
| SCHEMBL648227 | 0.88 | HDAC4 (0.48) | ALDH1A1USP2LMNANPSR1L3MBTL1 | |
| SCHEMBL8234112 | 0.87 | TP53 (0.45) | ALDH1A1HPGDHSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL8234439 | 0.86 | TP53 (0.45) | ALDH1A1HPGDHSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL8233770 | 0.85 | TP53 (0.43) | ALDH1A1HPGDHSD17B10HSP90AA1HSP90AB1 | |
| SCHEMBL8236747 | 0.83 | NPC1 (0.46) | ALDH1A1LMNAHPGDHSD17B10HSP90AA1 | |
| SCHEMBL8234043 | 0.83 | PLK1 (0.48) | LMNAHSD17B10HSP90AA1HSP90AB1THRB | |
| SCHEMBL8234051 | 0.80 | ALOX15 (0.49) | NPSR1L3MBTL1HSD17B10THRBMAPK1 | |
| SCHEMBL3103400 | 0.80 | RAB9A (0.45) | LMNAHSD17B10HSP90AA1HSP90AB1THRB | |
| SCHEMBL8236417 | 0.80 | RAB9A (0.51) | LMNANPSR1HPGDHSD17B10HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007109362-A2 | BENZOIMIDAZOLYL-PARAZINE COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-09-27 | — | — | WO | disclosed |