Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358159 | 0.82 | TSHR (0.42) | CES2CES1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3419470 | 0.82 | TSHR (0.39) | CES2CES1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL155657 | 0.82 | KMT2A (0.41) | CES2CES1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL10581003 | 0.82 | SMN1; SMN2 (0.45) | CES2CES1SMN1; SMN2TDP1TSHR | |
| SCHEMBL3183654 | 0.82 | HDAC1 (0.39) | CES2CES1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL24436952 | 0.82 | HSD17B1 (0.44) | — | |
| SCHEMBL7651439 | 0.81 | SMN1; SMN2 (0.40) | CES2CES1SMN1; SMN2TDP1TSHR | |
| SCHEMBL1931579 | 0.80 | TSHR (0.38) | CES2CES1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL22342670 | 0.80 | CES2 (0.38) | CES2CES1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8952179 | 0.80 | TSHR (0.38) | CES2CES1SMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119926191-B | Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119926191-A | Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119409630-A | Asymmetric polyfluoro-substituted 2,4' -biquinoline-4-amide derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2025-02-11 | — | — | CN | claimed |
| CN-114950159-B | Preparation method of aromatic polymer separation membrane based on super acid catalysis | 南京工业大学 | 2023-06-06 | — | — | CN | claimed |
| CN-114950159-A | Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation | 南京工业大学 | 2022-08-30 | — | — | CN | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| CN-119926191-B | Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-119926191-A | Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119409630-A | Asymmetric polyfluoro-substituted 2,4' -biquinoline-4-amide derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2025-02-11 | — | — | CN | disclosed |
| US-20240246968-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME LLC | 2024-07-25 | — | — | US | disclosed |
| CN-116693811-A | Cationic polymer containing condensed ring structure, and preparation method and application thereof | 合肥工业大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114950159-B | Preparation method of aromatic polymer separation membrane based on super acid catalysis | 南京工业大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-114950159-A | Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation | 南京工业大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-0154780-B1 | QUINOLINE ANTIBACTERIAL COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0298020-A1 | Use of an epoxidation reagent, and process for the preparation of 5-alpha (10-alpha) epoxy-delta 9(11) steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | disclosed |
| US-4774246-A | 6,8-DIFLUORO-4-OXO-3-CARBOXYLIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1988-09-27 | — | — | US | disclosed |
| EP-0154780-A1 | Quinoline antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-09-18 | — | — | EP | disclosed |
| EP-0004315-B1 | 1.1-DIPHENYLETHENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1981-02-25 | — | — | EP | disclosed |
| US-4213990-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| EP-0004315-A1 | 1.1-Diphenylethene derivatives, process for their preparation and their use as microbicides | CIBA-GEIGY AG (CH) | 1979-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246968-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | KRAS, NRAS, HRAS | CES2 4855/4885CES1 4246/4885SMN1; SMN2 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.