SCHEMBL823844

SCHEMBL823844

CC(=O)Oc1cc(F)c(F)c(F)c1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.47
CYP4A11 Q02928 2/20 0.47
TNFSF11 O14788 1/20 0.41
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.40
GAA P10253 2/20 0.40
RAB9A P51151 1/20 0.40
CFD P00746 2/20 0.39
HSD17B10 Q99714 4/20 0.38
HPGD P15428 3/20 0.38
POLB P06746 1/20 0.38
USP2 O75604 1/20 0.38
CYP2C19 P33261 1/20 0.38
GLA P06280 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
MAPT P10636 1/20 0.38
ALPG P10696 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31006941 1.00 CYP4F2 (0.47) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL12474133 0.84 CYP4F2 (0.45) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL24436820 0.84 CYP4F2 (0.45) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL474387 0.83 CES2 (0.39) CYP4F2CYP4A11MAPTCES2CES1
SCHEMBL7646091 0.82 ELANE (0.37) CYP4F2CYP4A11ALDH1A1GAARAB9A
SCHEMBL7711877 0.82 CYP4F2 (0.44) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL1998350 0.82 CYP4F2 (0.46) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL24445897 0.82 CYP4F2 (0.42) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1
SCHEMBL20156673 0.81 CES2 (0.38) CYP4F2CYP4A11RAB9APOLBLMNA
SCHEMBL24436812 0.80 CYP4F2 (0.45) CYP4F2CYP4A11TNFSF11KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118973617-A Conjugates, compositions, and methods of use 维尔托索宾科公司 2024-11-15 CN disclosed
EP-4460330-A1 CONJUGATES, COMPOSITIONS AND METHODS OF USE Virtuoso Binco, Inc. (US) 2024-11-13 EP disclosed
EP-4293112-A2 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF Genzyme Corporation (US) 2023-12-20 EP disclosed
EP-3597655-B1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORP (US) 2023-08-02 EP disclosed
WO-2023131219-A1 CONJUGATES, COMPOSITIONS AND METHODS OF USE VIRTUOSO BINCO, INC. (US) 2023-07-13 WO disclosed
US-20220204963-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION 2022-06-30 US disclosed
US-10907142-B2 Oligosaccharides comprising an aminooxy group and conjugates thereof GENZYME CORPORATION (US) 2021-02-02 US disclosed
EP-2457919-B1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORP (US) 2019-06-05 EP disclosed
EP-2457920-B1 Oligosaccharides comprising an aminooxy group and conjugates thereof GENZYME CORP (US) 2017-10-25 EP disclosed
WO-2017072662-A1 ANTIBODY CONJUGATES COMPRISING TOLL-LIKE RECEPTOR AGONIST NOVARTIS AG (CH) 2017-05-04 WO disclosed
US-20100284860-A1 MOLECULES SUITABLE FOR BINDING TO A METAL LAYER FOR COVALENTLY IMMOBILIZING BIOMOLECULES IMEC (BE) 2010-11-11 US disclosed
US-7770437-B2 Thiol or disulfide molecules having poly(ethylene oxide) groups for use in a self assembled monolayer bound to a metal layer for covalently immobilizing biomolecules in a biosensor IMEC (BE) 2010-08-10 US disclosed
US-7770437-B2 Thiol or disulfide molecules having poly(ethylene oxide) groups for use in a self assembled monolayer bound to a metal layer for covalently immobilizing biomolecules in a biosensor IMEC (BE) 2010-08-10 US disclosed
US-20100047225-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION (US) 2010-02-25 US disclosed
EP-2121713-A2 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF Genzyme Corporation (US) 2009-11-25 EP disclosed
EP-1798250-B1 Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules IMEC INTER UNI MICRO ELECTR (BE) 2008-09-03 EP disclosed
WO-2008089403-A2 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF GENZYME CORPORATION (US) 2008-07-24 WO disclosed
US-20070272003-A1 2-(2-{2-[2-(2-{2-[2-(11-mercaptoyldisulfanyl-undecyloxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy} acetic acid pentafluorophenyl ester; poly(ethylene oxide) groups resist nonspecific adsorption and enhance the specific affinity interactions IMEC (BE) 2007-11-29 US disclosed
US-20070272003-A1 2-(2-{2-[2-(2-{2-[2-(11-mercaptoyldisulfanyl-undecyloxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy} acetic acid pentafluorophenyl ester; poly(ethylene oxide) groups resist nonspecific adsorption and enhance the specific affinity interactions IMEC (BE) 2007-11-29 US disclosed
EP-1798250-A2 Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM vzw (IMEC) (BE) 2007-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10907142-B2 Oligosaccharides comprising an aminooxy group and conjugates thereof MAN2B1, MAN1B1, GAA CYP4F2 3324/4885CYP4A11 3392/4885TNFSF11 1147/4885
US-20220204963-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA CYP4F2 3324/4885CYP4A11 3392/4885TNFSF11 1147/4885
US-20100047225-A1 OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF MAN2B1, MAN1B1, GAA CYP4F2 3324/4885CYP4A11 3392/4885TNFSF11 1147/4885
US-20100284860-A1 MOLECULES SUITABLE FOR BINDING TO A METAL LAYER FOR COVALENTLY IMMOBILIZING BIOMOLECULES EBPL, SPR, MB CYP4F2 2365/4885CYP4A11 4804/4885TNFSF11 476/4885
US-20070272003-A1 2-(2-{2-[2-(2-{2-[2-(11-mercaptoyldisulfanyl-undecyloxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy} acetic acid pentafluorophenyl ester; poly(ethylene oxide) groups resist nonspecific adsorption and enhance the specific affinity interactions EBPL, AEBP2, NAPA CYP4F2 1008/4885CYP4A11 4322/4885TNFSF11 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.