Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235446 | 0.72 | HPGD (0.56) | ALDH1A1GAAKMT2AHTTL3MBTL1 | |
| SCHEMBL9831692 | 0.72 | CHKA (0.39) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10810138 | 0.71 | ALDH1A1 (0.47) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6223137 | 0.70 | GAA (0.65) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6273294 | 0.70 | GAA (0.65) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8864170 | 0.70 | GAA (0.65) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6826402 | 0.70 | HPGD (0.50) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL20043806 | 0.70 | S100B (0.65) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5789028 | 0.69 | HRH4 (0.57) | S100BALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16056360 | 0.69 | ALDH1A1 (0.49) | S100BALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072041-A1 | THERAPEUTIC COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |