Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608667 | 0.88 | EPHX2 (0.46) | EPHX2KMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL29561956 | 0.87 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL29401210 | 0.87 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL118052 | 0.87 | EPHX2 (0.63) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL15948140 | 0.86 | EPHX2 (0.57) | EPHX2KMT2A | |
| SCHEMBL15948141 | 0.86 | EPHX2 (0.57) | EPHX2KMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL15939984 | 0.86 | EPHX2 (0.62) | EPHX2KMT2AFABP7FABP5MDM4 | |
| SCHEMBL30833078 | 0.86 | EPHX2 (0.62) | EPHX2KMT2AFABP7FABP5 | |
| SCHEMBL3212121 | 0.85 | EPHX2 (0.56) | EPHX2KMT2AHDAC2HDAC8HDAC6 | |
| SCHEMBL15946357 | 0.85 | EPHX2 (0.56) | EPHX2KMT2ANPSR1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152188-A1 | Novel Heterocyclic Compounds | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-06-17 | — | — | US | disclosed |
| US-20100152188-A1 | Novel Heterocyclic Compounds | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-06-17 | — | — | US | disclosed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152188-A1 | Novel Heterocyclic Compounds | CYP11B2, CYP3A5, CYP11B1 | EPHX2 1202/4885KMT2A 4019/4885HDAC2 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.