Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.61 |
| ▸ | KDM1A | O60341 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605533 | 0.86 | HDAC1 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL6572354 | 0.84 | HDAC6 (0.72) | HDAC1KDM1AHDAC6HDAC3HDAC2 | |
| SCHEMBL8248437 | 0.80 | HDAC6 (0.62) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8240953 | 0.78 | HDAC6 (0.65) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL8245700 | 0.77 | HDAC1 (0.56) | HDAC1KDM1AHDAC6HDAC3HDAC2 | |
| SCHEMBL8248244 | 0.77 | HDAC6 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL14880225 | 0.76 | CES2 (0.64) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL27605535 | 0.76 | HDAC1 (1.00) | HDAC1KDM1AHDAC6HDAC3HDAC2 | |
| SCHEMBL3455877 | 0.76 | LSS (0.69) | HDAC1KDM1AHDAC6HDAC3HDAC8 | |
| SCHEMBL4497840 | 0.76 | LSS (0.69) | HDAC1KDM1AHDAC6HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152188-A1 | Novel Heterocyclic Compounds | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-06-17 | — | — | US | disclosed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152188-A1 | Novel Heterocyclic Compounds | CYP11B2, CYP3A5, CYP11B1 | HDAC1 307/4885KDM1A 4273/4885HDAC6 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.