Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13361307 | 0.92 | MEN1 (0.36) | MEN1KMT2AMGLLALDH1A1MAPT | |
| SCHEMBL3859077 | 0.90 | MEN1 (0.35) | MEN1KMT2AMGLLALDH1A1MAPT | |
| SCHEMBL3859082 | 0.90 | MEN1 (0.35) | MEN1KMT2ACYP1A2CYP2C19MGLL | |
| SCHEMBL13331377 | 0.89 | FPR3 (0.37) | MEN1KMT2AMGLLALDH1A1MAPT | |
| SCHEMBL8233817 | 0.85 | NPC1 (0.39) | MEN1KMT2AALDH1A1MAPTFPR3 | |
| SCHEMBL13361408 | 0.82 | MGLL (0.35) | MGLLALDH1A1MAPTMCHR1MMP1 | |
| SCHEMBL3866342 | 0.81 | MGLL (0.34) | MGLLALDH1A1MCHR1MMP1MMP2 | |
| SCHEMBL8242485 | 0.81 | CYP1A2 (0.36) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13331379 | 0.79 | MGLL (0.33) | MGLLMCHR1MMP1MMP2MMP9 | |
| SCHEMBL3868115 | 0.79 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1MAPTFPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |