Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | CALML3 | P27482 | 1/20 | 0.53 |
| ▸ | SDHA | P31040 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480971 | 0.85 | BPTF (0.57) | BPTFF10KDM4ERXFP1TP53 | |
| SCHEMBL13263368 | 0.82 | MAOB (0.72) | BPTFMAOBMAOALMNAPTGS1 | |
| SCHEMBL1336215 | 0.81 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL76846 | 0.81 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5513933 | 0.81 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL29439547 | 0.81 | MAOB (0.69) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8364779 | 0.79 | MAOB (0.50) | BPTFMAOBMAOALMNAPTGS1 | |
| SCHEMBL13368000 | 0.78 | BPTF (0.55) | BPTFMAOBMAOALMNAPTGS1 | |
| Acetic Acid SCHEMBL1338393 | 0.76 | MAOB (0.74) | MAOBMAOALMNAPTGS1CALML3 | |
| Acetic Acid SCHEMBL1338391 | 0.76 | MAOB (0.74) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042146-A1 | MICROANGIOPATHY TREATMENT AND PREVENTION | BAYER HEALTHCARE AG (DE) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007039134-A1 | COMBINATION THERAPY COMPRISING SUBSTITUTED OXAZOLIDINONES FOR THE PREVENTION AND TREATMENT OF CEREBRAL CIRCULATORY DISORDERS | BAYER HEALTHCARE AG (DE) | 2007-04-12 | — | — | WO | disclosed |
| WO-2003000256-A1 | SUBSTITUTED OXAZOLIDINONES FOR COMBINATIONAL THERAPY | BAYER HEALTHCARE AG (DE) | 2003-01-03 | — | — | WO | disclosed |