Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252581 | 0.76 | ABCB1 (0.39) | PIK3CDABCB1ALDH1A1PSEN1PSEN2 | |
| SCHEMBL8259949 | 0.75 | ABCB1 (0.40) | ABCB1RBP4ALDH1A1PSEN1PSEN2 | |
| SCHEMBL8259151 | 0.75 | ABCB1 (0.40) | ABCB1RBP4ALDH1A1PSEN1PSEN2 | |
| SCHEMBL7193232 | 0.71 | RBP4 (0.42) | PIK3CDABCB1RBP4ALDH1A1POLB | |
| SCHEMBL8238415 | 0.71 | RBP4 (0.42) | PIK3CDABCB1RBP4ALDH1A1POLB | |
| SCHEMBL9706890 | 0.71 | RBP4 (0.42) | PIK3CDABCB1RBP4ALDH1A1POLB | |
| SCHEMBL8232622 | 0.69 | PARP1 (0.42) | PIK3CDABCB1RBP4ALDH1A1POLB | |
| SCHEMBL7558692 | 0.69 | PARP1 (0.42) | PIK3CDABCB1RBP4ALDH1A1POLB | |
| SCHEMBL7558696 | 0.69 | PARP1 (0.42) | PIK3CDABCB1RBP4ALDH1A1POLB | |
| SCHEMBL10816146 | 0.66 | KMT2A (0.39) | RBP4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007052134-A1 | (2S)-2-AMINOMETHYL-5-ETHYL HEPTANOIC ACID ITS PHARMACEUTICAL USE | PFIZER LIMITED (GB) | 2007-05-10 | — | — | WO | disclosed |