Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259949 | 1.00 | ABCB1 (0.40) | ABCB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8252581 | 0.86 | ABCB1 (0.39) | ABCB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8240935 | 0.75 | PIK3CD (0.36) | ABCB1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7193232 | 0.68 | RBP4 (0.42) | ABCB1KMT2ANPC1RAB9ARBP4 | |
| SCHEMBL9706890 | 0.68 | RBP4 (0.42) | ABCB1KMT2ANPC1RAB9ARBP4 | |
| SCHEMBL8238415 | 0.68 | RBP4 (0.42) | ABCB1KMT2ANPC1RAB9ARBP4 | |
| SCHEMBL31518796 | 0.67 | CARM1 (0.42) | CA2CA9MMP2SIGMAR1 | |
| SCHEMBL7558692 | 0.66 | PARP1 (0.42) | ABCB1KMT2AMEN1RBP4ALDH1A1 | |
| SCHEMBL8232622 | 0.66 | PARP1 (0.42) | ABCB1KMT2AMEN1RBP4ALDH1A1 | |
| SCHEMBL7558696 | 0.66 | PARP1 (0.42) | ABCB1KMT2AMEN1RBP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006120544-A1 | β-AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-16 | — | — | WO | disclosed |