Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.41 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964715 | 0.84 | MAPT (0.48) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| SCHEMBL8241703 | 0.84 | MAPT (0.48) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| Bromide SCHEMBL11023029 | 0.77 | HCAR3 (0.52) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| Bromide SCHEMBL11509451 | 0.77 | HCAR3 (0.52) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| Bromide SCHEMBL11097137 | 0.77 | MAPT (0.58) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| SCHEMBL8234393 | 0.76 | CD44 (0.43) | CYP1A2CYP2C19CYP2C9MEN1KMT2A | |
| SCHEMBL26350270 | 0.74 | BRD4 (0.40) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| SCHEMBL4647601 | 0.74 | ALDH1A1 (0.48) | MAPTHTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL29077669 | 0.74 | BRD4 (0.44) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| SCHEMBL865610 | 0.74 | MAPT (0.45) | MAPTCYP1A2CYP2C19CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036718-A2 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |