Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828827 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL798209 | 0.83 | GAA (0.41) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL773587 | 0.83 | GAA (0.41) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL27708516 | 0.81 | TP53 (0.36) | GAAMGAMSIMGAM2HSD17B10 | |
| SCHEMBL7515086 | 0.80 | GAA (0.46) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL1660371 | 0.79 | GAA (0.44) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL4603085 | 0.77 | GAA (0.43) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL3903468 | 0.77 | GAA (0.43) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL18573883 | 0.77 | CYP1A2 (0.44) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL16753659 | 0.77 | GAA (0.48) | ALDH1A1TRPA1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
| WO-2007045367-A1 | CYCLOPROPYLACETIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | PCCA, PPP2CA, HMGCR | ALDH1A1 524/4885TRPA1 4224/4885GAA 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.