Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212418 | 0.86 | TAAR1 (0.49) | TAAR1HPGDMAPK1FPR2EPHX2 | |
| SCHEMBL16357069 | 0.78 | NPC1 (0.55) | MAPTSMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL8215633 | 0.72 | KIF11 (0.50) | HPGDFPR2EPHX2MAPTKMT2A | |
| SCHEMBL8208836 | 0.72 | MEN1 (0.52) | HPGDMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8212593 | 0.72 | SMN1; SMN2 (0.47) | FPR2MAPTKMT2ANPSR1USP2 | |
| SCHEMBL12156920 | 0.72 | MAPT (0.49) | HPGDEPHX2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8243200 | 0.71 | MAPT (0.41) | FPR2EPHX2MAPTKMT2ANPSR1 | |
| SCHEMBL14494432 | 0.71 | MAPT (0.41) | FPR2EPHX2MAPTKMT2ANPSR1 | |
| SCHEMBL12259230 | 0.69 | HPGD (0.74) | HPGDMAPK1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8215800 | 0.67 | TAAR1 (0.63) | TAAR1HPGDMAPTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064732-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |