Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234393 | 0.78 | CD44 (0.43) | HTR4ALDH1A1 | |
| SCHEMBL6154542 | 0.76 | HTR4 (0.58) | HTR4ALDH1A1HTTDRD4DDR1 | |
| Hydrochloric Acid SCHEMBL6154062 | 0.75 | HTR4 (0.57) | HTR4ALDH1A1HTTDRD4DDR1 | |
| SCHEMBL4646693 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HTTNPC1NSD2EHMT2 | |
| SCHEMBL18970134 | 0.72 | HTR4 (0.45) | HTR4ALDH1A1HTR2CTSHRNSD2 | |
| SCHEMBL22725031 | 0.72 | IKBKB (0.42) | GAAALDH1A1HTR2AHTR2CTSHR | |
| SCHEMBL1673520 | 0.70 | HTR2C (0.54) | ALDH1A1HTR2C | |
| SCHEMBL4965097 | 0.70 | BRD4 (0.41) | HTR4ALDH1A1 | |
| SCHEMBL7053215 | 0.70 | CYP1A2 (0.47) | ALDH1A1HTR2CDDR1 | |
| SCHEMBL92047 | 0.69 | GAA (1.00) | GAAALDH1A1HTTNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007036718-A2 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |