Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121049 | 0.97 | LTA4H (0.65) | LTA4HSIGMAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL31305362 | 0.89 | LTA4H (0.71) | LTA4HSIGMAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL30997860 | 0.88 | LTA4H (0.57) | LTA4HSIGMAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL11100043 | 0.86 | SIGMAR1 (0.71) | LTA4HSIGMAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL26981197 | 0.85 | LTA4H (0.75) | LTA4HSIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL19557301 | 0.85 | LTA4H (0.75) | LTA4HSIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL28558914 | 0.83 | SIGMAR1 (0.77) | LTA4HSIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL29447351 | 0.82 | LTA4H (0.87) | LTA4HSIGMAR1KDM4EALDH1A1MEN1 | |
| SCHEMBL22266156 | 0.81 | LTA4H (0.65) | LTA4HSIGMAR1KDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9646857 | 0.81 | LTA4H (0.51) | LTA4HSIGMAR1KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004234-A1 | A PROCESS FOR THE PREPARATION OF 2-[2-(4-DIBENZO[b,f] [L,4] THIAZEPIN-11-yl-1- PIPERAZINYL)ETHOXY] ETHANOL FUMARATE | USV LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |