Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833902 | 0.87 | KDM4E (0.55) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL20798351 | 0.83 | XDH (0.55) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL29467240 | 0.83 | XDH (0.55) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL31214529 | 0.81 | ALDH1A1 (0.60) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| Alloxazine SCHEMBL499075 | 0.77 | KDM4E (1.00) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| Alloxazine SCHEMBL29516835 | 0.77 | KDM4E (1.00) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL10983379 | 0.76 | KDM4E (0.74) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL3225296 | 0.76 | KDM4E (0.74) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL824381 | 0.76 | PIK3CG (0.56) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A | |
| SCHEMBL11087373 | 0.75 | KDM4E (0.69) | PIK3CGKDM4EALDH1A1HSD17B10ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071903-B1 | DIGLYCIDYL PTERIDINE COMPOUNDS, METHOD FOR THEIR PREPARATION AND THEIR USE IN DRUGS WITH A CYTOSTATIC ACTIVITY | Henkel Kommanditgesellschaft auf Aktien (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4463006-A | ANTICANCER, ANTITUMOR AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1984-07-31 | — | — | US | disclosed |
| EP-0071903-A1 | Diglycidyl pteridine compounds, method for their preparation and their use in drugs with a cytostatic activity | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-02-16 | — | — | EP | disclosed |