SCHEMBL8244141

SCHEMBL8244141

O=C(O)CN(CCNCCN(CC(=O)O)CC(=O)O)CC(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.65
EYA2 O00167 1/20 0.65
APP P05067 1/20 0.65
ACE P12821 1/20 0.65
BLM P54132 2/20 0.62
PMP22 Q01453 2/20 0.62
KDM4E B2RXH2 1/20 0.62
LMNA P02545 1/20 0.62
CHRM2 P08172 1/20 0.62
ADRA2A P08913 1/20 0.62
ALOX15 P16050 1/20 0.62
TSHR P16473 1/20 0.62
DRD1 P21728 1/20 0.62
SLC6A2 P23975 1/20 0.62
SLC6A4 P31645 1/20 0.62
CYP2C19 P33261 1/20 0.62
ADRA1A P35348 1/20 0.62
DRD3 P35462 1/20 0.62
SLC6A3 Q01959 1/20 0.62
HRH3 Q9Y5N1 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625926 0.91 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL20183298 0.89 TDP1 (0.52) TDP1EYA2APPACEBLM
SCHEMBL10385583 0.89 TDP1 (0.52) TDP1EYA2APPACEBLM
SCHEMBL111010 0.88 TDP1 (0.56) TDP1EYA2APPACEBLM
SCHEMBL9714346 0.87 TDP1 (0.50) TDP1EYA2APPACEBLM
SCHEMBL8968772 0.87 TDP1 (0.50) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL1077971 0.86 TDP1 (0.61) TDP1EYA2APPACEBLM
SCHEMBL11797447 0.86 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL18793625 0.86 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL18335460 0.85 TDP1 (0.48) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-08-28 US claimed
CN-120121830-A Agkistrodon acutus venom detection kit and detection method thereof 广西医科大学第一附属医院 2025-06-10 CN claimed
CN-120121831-A High-sensitivity detection method and kit for urine soluble CD163 浙江理工大学 2025-06-10 CN claimed
EP-4522619-A1 PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM OLON S.p.A. (IT) 2025-03-19 EP claimed
EP-4511365-A1 PROCESSES FOR THE PREPARATION OF FINERENONE Teva Pharmaceuticals International GmbH (CH) 2025-02-26 EP claimed
EP-4479546-A2 PROCESSES FOR PREPARATION OF AVACOPAN AND INTERMEDIATES THEREOF Teva Pharmaceuticals International GmbH (CH) 2024-12-25 EP claimed
CN-118878768-A Thienyl COF material, synthesis method thereof and iodine adsorption application 陕西科技大学 2024-11-01 CN claimed
CN-118878538-A Novel preparation method of green lumepiquat chloride 江苏宝东医药科技有限公司 2024-11-01 CN claimed
WO-2024224426-A1 PROCESS FOR THE PREPARATION OF 7-CHLORO-6-FLUORO-(1M)-1-[4-METHYL-2-(PROPAN-2-YL)PYRIDIN-3-YL]PYRIDO[2,3-D] PYRIMIDINE-2,4(1H,3H)-DIONE (M-DIONE) NATCO PHARMA LIMITED (IN) 2024-10-31 WO claimed
EP-4063433-B1 HYDROGEL OF MERCAPTO-MODIFIED MACROMOLECULAR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF BLAFAR BIOTECHNOLOGY HANGZHOU LTD (CN) 2024-09-04 EP claimed
WO-2022252012-A1 TUMOR DIAGNOSIS AND TREATMENT AGENT, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳先进技术研究院 2022-12-08 WO claimed
CN-115144585-A ST2 detection method based on magnetic particle time-resolved fluoroimmunoassay 浙江理工大学 2022-10-04 CN claimed
EP-4063433-A1 HYDROGEL OF MERCAPTO-MODIFIED MACROMOLECULAR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Blafar Biotechnology (Hangzhou) Ltd. (CN) 2022-09-28 EP claimed
CN-115078708-A Pancreatic stone protein detection method based on magnetic particle time-resolved fluorescence immunoassay 浙江理工大学 2022-09-20 CN claimed
CN-114717036-A Preparation method of ashless dispersant 中国石油天然气股份有限公司 2022-07-08 CN claimed
CN-113717176-B Method for preparing remazolam 上海再启生物技术有限公司 2022-07-05 CN claimed
CN-110981901-B Purification method of amino-terminated siloxane 上海彩迩文生化科技有限公司 2022-07-05 CN claimed
CN-114686019-A Improved production process of PR122 浙江永泉化学有限公司 2022-07-01 CN claimed
CN-114314560-A Preparation method of gadolinium-doped mesoporous carbon sphere nanoparticles 徐州医科大学 2022-04-12 CN claimed
US-11279685-B2 Enantiomeric separation of racemic nicotine by addition of an O,O″-disubstituted tartaric acid enantiomer SIEGFRIED AG (CH) 2022-03-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279685-B2 Enantiomeric separation of racemic nicotine by addition of an O,O″-disubstituted tartaric acid enantiomer CHRNB1, CHRNA1, CHRM1 TDP1 316/4885EYA2 3631/4885APP 2589/4885
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE CYP11B1, CYP11B2, HSD17B7 TDP1 1814/4885EYA2 1336/4885APP 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.