SCHEMBL824436

SCHEMBL824436

NS(=O)(=O)c1cc2c3c(cccc3c1)-c1nc3cc(C(=O)O)ccc3nc1-2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PKM P14618 1/20 0.55
HTT P42858 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
ALDH1A1 P00352 5/20 0.48
HPGD P15428 4/20 0.48
GAA P10253 3/20 0.48
KDM4E B2RXH2 3/20 0.48
NPC1 O15118 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CSNK2A2 P19784 2/20 0.44
CSNK2B P67870 2/20 0.44
MAPT P10636 3/20 0.43
NSD2 O96028 1/20 0.43
POLB P06746 1/20 0.43
THRB P10828 1/20 0.43
PABPC1 P11940 1/20 0.43
TNNI3 P19429 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824444 1.00 RAB9A (0.55) RAB9AMEN1KMT2APKMHTT
SCHEMBL14845570 0.92 RAB9A (0.54) RAB9AMEN1KMT2APKMHTT
SCHEMBL2395393 0.89 MEN1 (0.56) RAB9AMEN1KMT2APKMHTT
SCHEMBL2396254 0.89 MEN1 (0.56) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2395604 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2395606 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2396272 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
Ammonia Solution, Strong SCHEMBL2396268 0.88 MEN1 (0.55) RAB9AMEN1KMT2APKMHTT
SCHEMBL14336345 0.87 RAB9A (0.50) RAB9AMEN1KMT2APKMHTT
SCHEMBL3215265 0.85 RAB9A (0.65) RAB9AMEN1KMT2APKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895118-B2 Negative dispersion retardation plate and achromatic circular polarizer CRYSOPTIX K.K. (JP) 2014-11-25 US disclosed
US-8416376-B2 Compensated in-plane switching mode liquid crystal display CRYSOPTIX KK (JP) 2013-04-09 US disclosed
US-8416376-B2 Compensated in-plane switching mode liquid crystal display CRYSOPTIX KK (JP) 2013-04-09 US disclosed
US-20120113380-A1 NEGATIVE DISPERSION RETARDATION PLATE AND ACHROMATIC CIRCULAR POLARIZER CRYSOPTIX KK (JP) 2012-05-10 US disclosed
US-8142863-B2 Color liquid crystal display and compensation panel Crysoptix, KK (JP) 2012-03-27 US disclosed
US-8142863-B2 Color liquid crystal display and compensation panel Crysoptix, KK (JP) 2012-03-27 US disclosed
US-7889297-B2 Liquid crystal display operating in a vertically aligned mode Crysoptix, KK (JP) 2011-02-15 US disclosed
US-20100149471-A1 Compensated In-Plane Switching Mode Liquid Crystal Display CRYSOPTIX KK (JP) 2010-06-17 US disclosed
US-20100118241-A1 Liquid Crystal Display Operating in a Vertically Aligned Mode CRYSOPTIX KK (JP) 2010-05-13 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090268136-A1 Color Liquid Crystal Display and Compensation Panel CRYSOPTIX KK (JP) 2009-10-29 US disclosed
US-20090191394-A1 Oarganic Compound, Optical Crystal Film and Method of Production Thereof CRYSOPTIX K.K. (JP) 2009-07-30 US disclosed
US-20090161037-A1 Backlight Module and Liquid Crystal Display Incorporating the Same CRYSOPTIX KK (JP) 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090191394-A1 Oarganic Compound, Optical Crystal Film and Method of Production Thereof HCN3, CFH, KCNH1 RAB9A 1824/4885MEN1 1151/4885KMT2A 1897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.