Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270512 | 0.90 | CTSS (0.45) | CTSLCTSSCTSKCTSBMAPK8 | |
| SCHEMBL8243947 | 0.89 | CTSL (0.56) | CTSLCTSSCTSKCTSBMAPK8 | |
| SCHEMBL8243088 | 0.89 | CTSL (0.46) | CTSLCTSSCTSKCTSBMAPK8 | |
| Trifluoroacetic Acid SCHEMBL5792187 | 0.86 | CTSS (0.41) | CTSLCTSSCTSKCTSBMAPK8 | |
| SCHEMBL8245231 | 0.83 | CTSL (0.46) | CTSLCTSSCTSKCTSBALDH1A1 | |
| SCHEMBL5794190 | 0.82 | ALDH1A1 (0.41) | CTSLCTSSCTSKCTSBMAPK8 | |
| SCHEMBL8245916 | 0.81 | CTSL (0.46) | CTSLCTSSCTSKCTSBHTT | |
| SCHEMBL5309362 | 0.77 | CTSL (0.42) | CTSLCTSSCTSKCTSB | |
| SCHEMBL8246096 | 0.75 | CTSL (0.41) | CTSLCTSSCTSKCTSBPOLB | |
| SCHEMBL8245772 | 0.74 | CTSL (0.49) | CTSLCTSSCTSKCTSBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |