⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141817 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL14042410 | 0.69 | KDM4E (0.33) | — | |
| SCHEMBL11923092 | 0.63 | — | — | |
| SCHEMBL13079837 | 0.62 | KDM4E (0.37) | — | |
| SCHEMBL7902797 | 0.58 | — | — | |
| SCHEMBL8141903 | 0.58 | ALDH1A1 (0.30) | — | |
| SCHEMBL2283153 | 0.57 | MGLL (0.39) | — | |
| SCHEMBL21563102 | 0.56 | — | — | |
| SCHEMBL8138983 | 0.55 | ALDH1A1 (0.37) | — | |
| SCHEMBL1943173 | 0.55 | L3MBTL1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960389-B1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LTD (GB) | 2012-08-15 | — | — | EP | disclosed |
| EP-1943230-B1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LTD (GB) | 2010-12-22 | — | — | EP | disclosed |
| WO-2007036711-A1 | BENZIMIDAZOLONES WHICH HAVE ACTIVITY AT Ml RECEPTOR | GLAXO GROUP LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |