Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.58 |
| ▸ | MMP8 | P22894 | 7/20 | 0.58 |
| ▸ | MMP1 | P03956 | 4/20 | 0.58 |
| ▸ | CCKBR | P32239 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 5/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | CCKAR | P32238 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242675 | 1.00 | MMP2 (0.58) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL8242694 | 0.97 | CCKBR (0.61) | MMP2MMP8MMP1CCKBRCCKAR | |
| SCHEMBL8235648 | 0.96 | MMP2 (0.62) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL8235720 | 0.94 | MMP1 (0.56) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL14177510 | 0.94 | CCKBR (0.61) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL8236310 | 0.94 | MMP2 (0.51) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL8363817 | 0.93 | MMP2 (0.62) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL8242045 | 0.93 | EDNRA (0.55) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL8236296 | 0.92 | MMP2 (0.59) | MMP2MMP8MMP1CCKBRMMP9 | |
| SCHEMBL14186778 | 0.92 | MMP2 (0.59) | MMP2MMP8MMP1CCKBRMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119395-A1 | Novel Depsipeptides and Process for Preparing Same | CUBIST PHARMACEUTICALS, INC. | 2008-05-22 | — | — | US | disclosed |
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | CUBIST PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | VIP, DNPEP, PREP | MMP2 1509/4885MMP8 1241/4885MMP1 3140/4885 |
| US-20080119395-A1 | Novel Depsipeptides and Process for Preparing Same | VIP, DNPEP, PREP | MMP2 1509/4885MMP8 1241/4885MMP1 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.