Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28073195 | 0.85 | MAPT (0.36) | MAPTPKMKDM4EFKBP1AALDH1A1 | |
| SCHEMBL3316200 | 0.83 | MAPT (0.39) | MAPTPKMFKBP1AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL31127906 | 0.81 | MAPT (0.37) | MAPTPKMKDM4EFKBP1AALDH1A1 | |
| SCHEMBL12616606 | 0.81 | LMNA (0.33) | KCNK3LMNA | |
| Piperazine SCHEMBL28081240 | 0.80 | MAPT (0.37) | MAPTPKMFKBP1AALDH1A1LMNA | |
| SCHEMBL1740752 | 0.77 | MEN1 (0.53) | MAPTPKMKDM4EALDH1A1 | |
| SCHEMBL4532848 | 0.77 | FKBP1A (0.38) | MAPTPKMFKBP1AALDH1A1LMNA | |
| SCHEMBL8025147 | 0.77 | FKBP1A (0.38) | MAPTPKMFKBP1AALDH1A1LMNA | |
| SCHEMBL18948659 | 0.76 | KDM4E (0.51) | MAPTKDM4EFKBP1AALDH1A1KCNK3 | |
| SCHEMBL8718223 | 0.76 | MAPT (0.36) | MAPTPKMKDM4EFKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028654-A1 | PYRIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | disclosed |