Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.94 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.67 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | EDNRA | P25101 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316335 | 0.97 | ACHE (1.00) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL29598156 | 0.97 | ACHE (1.00) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL38655977 | 0.93 | ACHE (0.89) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL21083730 | 0.88 | ACHE (0.82) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL6533118 | 0.86 | ACHE (0.80) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL21083538 | 0.85 | ACHE (0.79) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL21083862 | 0.85 | ACHE (0.77) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL13539765 | 0.85 | ACHE (0.77) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL21083894 | 0.84 | ACHE (0.76) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL21083812 | 0.84 | ACHE (0.76) | ACHEAGTR1LTB4R2ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964737-B2 | Angiotensin II receptor antagonist; industrially viable, recoverable and reusable; Irbesartan | JUBILANT ORGANOSYS LIMITED (IN) | 2011-06-21 | — | — | US | disclosed |
| US-7964737-B2 | Angiotensin II receptor antagonist; industrially viable, recoverable and reusable; Irbesartan | JUBILANT ORGANOSYS LIMITED (IN) | 2011-06-21 | — | — | US | disclosed |
| US-20080214830-A1 | Process for Producing 2-(N-Butyl)-3-[[2'-(Tetrazol-5-Yl)Biphenyl-4-Yl]Methyl]-I,3-Diazaspiro[4,4] Non-1-En-4-One | JUBILANT ORGANOSYS LIMITED (IN) | 2008-09-04 | — | — | US | disclosed |
| US-20080214830-A1 | Process for Producing 2-(N-Butyl)-3-[[2'-(Tetrazol-5-Yl)Biphenyl-4-Yl]Methyl]-I,3-Diazaspiro[4,4] Non-1-En-4-One | JUBILANT ORGANOSYS LIMITED (IN) | 2008-09-04 | — | — | US | disclosed |
| WO-2007013101-A1 | PROCESS FOR PRODUCING 2-(N-BUTYL)-3-[[2'-(TETRAZOL-5-YL)BIPHENYL- 4-YL]METHYL]-l,3-DIAZASPIRO[4.4] NON-1-EN-4-ONE | JUBILANT ORGANOSYS LIMITED (IN) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214830-A1 | Process for Producing 2-(N-Butyl)-3-[[2'-(Tetrazol-5-Yl)Biphenyl-4-Yl]Methyl]-I,3-Diazaspiro[4,4] Non-1-En-4-One | CYP4B1, NONO, ENO1 | ACHE 1430/4885AGTR1 2594/4885LTB4R2 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.