Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 1.00 |
| ▸ | CTSS | P25774 | 9/20 | 1.00 |
| ▸ | CTSL | P07711 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168737 | 0.80 | CTSK (0.67) | CTSKCTSSCTSLMMP13ADAMTS4 | |
| SCHEMBL6215843 | 0.79 | CTSK (0.83) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4714161 | 0.79 | CTSK (0.83) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7163658 | 0.78 | CTSK (0.64) | CTSKCTSSCTSLMMP13ADAMTS4 | |
| SCHEMBL7160493 | 0.76 | CTSK (0.62) | CTSKCTSSCTSLCTSBMMP13 | |
| SCHEMBL7248570 | 0.76 | CTSK (0.61) | CTSKCTSSMMP13ADAMTS4MMP1 | |
| SCHEMBL5934588 | 0.76 | CTSK (0.63) | CTSKCTSSCTSLCTSBMMP13 | |
| SCHEMBL7165313 | 0.75 | MMP13 (0.60) | CTSKCTSSCTSLCTSBMMP13 | |
| SCHEMBL7163603 | 0.75 | CTSK (0.60) | CTSKCTSSCTSLCTSBMMP13 | |
| SCHEMBL7248005 | 0.74 | CTSK (0.59) | CTSKCTSSMMP13ADAMTS4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041775-A1 | CYSTEINE PROTEASE INHIBITORS INCORPORATING AZIDE GROUPS | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-04-19 | — | — | WO | disclosed |