Sugi Predict

Sugi Predict / Compounds / SCHEMBL679340

SCHEMBL679340

SCHEMBL679340

CC1(C)OC(=O)C(Cc2ccc([N+](=O)[O-])cc2)(Cc2ccc([N+](=O)[O-])cc2)C(=O)O1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LOXL2 Q9Y4K0 1/20 0.46
▸ KMT2A Q03164 3/20 0.45
▸ LMNA P02545 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ HTT P42858 1/20 0.45
▸ KDM4E B2RXH2 2/20 0.44
▸ TSHR P16473 1/20 0.43
▸ IDO1 P14902 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ MAPT P10636 1/20 0.42
▸ KCNJ1 P48048 1/20 0.42
▸ ACHE P22303 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ CYP2C19 P33261 3/20 0.41
▸ POLB P06746 2/20 0.41
▸ NR3C1 P04150 1/20 0.41
▸ PGR P06401 1/20 0.41
▸ AR P10275 1/20 0.41
▸ CRHBP P24387 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10195636 0.90 LMNA (0.42) LOXL2KMT2ALMNASMN1; SMN2MEN1
SCHEMBL12786634 0.89 GAA (0.42) KMT2ALMNASMN1; SMN2MEN1HTT
SCHEMBL13495621 0.88 KMT2A (0.38) LOXL2KMT2ALMNASMN1; SMN2MEN1
SCHEMBL23056749 0.77 GFER (0.37) LOXL2LMNASMN1; SMN2TSHRALDH1A1
SCHEMBL16174713 0.77 ELANE (0.44) KMT2AHTTALDH1A1CYP2C19CYP1A2
SCHEMBL17171326 0.75 MEN1 (0.39) LOXL2KMT2ALMNASMN1; SMN2MEN1
SCHEMBL3091631 0.74 GLA (0.61) LOXL2KMT2ALMNAMEN1TSHR
SCHEMBL1204527 0.72 LOXL2 (0.48) LOXL2LMNASMN1; SMN2KDM4ETSHR
SCHEMBL8247259 0.72 TSHR (0.46) LOXL2KMT2ATSHRIDO1KCNJ1
SCHEMBL14788909 0.71 KDM4E (0.61) LOXL2KMT2ALMNASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210061782-A1 Diamine Compound with Meldrum's Acid Group and Related Polymer Thereof NATIONAL TSING HUA UNIVERSITY (TW) 2021-03-04 — — US disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 — — US disclosed
US-10197881-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2019-02-05 — — US disclosed
US-20170362381-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2017-12-21 — — US disclosed
US-20170362381-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2017-12-21 — — US disclosed
US-20170184936-A1 Complimentary Polymer Electrochromic Device ASHWIN-USHAS CORP INC (US) 2017-06-29 — — US disclosed
US-20170184936-A1 Complimentary Polymer Electrochromic Device ASHWIN-USHAS CORP INC (US) 2017-06-29 — — US disclosed
EP-2780762-B1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORP INC (US) 2017-06-28 — — EP disclosed
EP-2780762-B1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORP INC (US) 2017-06-28 — — EP disclosed
US-9594284-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2017-03-14 — — US disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 — — US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 — — WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 — — EP disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 — — EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 — — WO disclosed
EP-1801097-A1 Photocrosslinkable materials Rolic AG (CH) 2007-06-27 — — EP disclosed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 — — US disclosed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 — — EP disclosed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 — — WO disclosed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 LOXL2 1264/4885KMT2A 770/4885LMNA 590/4885
US-20210061782-A1 Diamine Compound with Meldrum's Acid Group and Related Polymer Thereof DDC, DAO, TLR5 LOXL2 1390/4885KMT2A 119/4885LMNA 3702/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD LOXL2 2938/4885KMT2A 666/4885LMNA 2057/4885
US-10197881-B2 Complimentary polymer electrochromic device PMS2, PARG, EED LOXL2 653/4885KMT2A 692/4885LMNA 3263/4885
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO LOXL2 1394/4885KMT2A 511/4885LMNA 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.