Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966349 | 0.82 | — | — | |
| SCHEMBL4252942 | 0.79 | GPR84 (0.31) | GPR84 | |
| SCHEMBL22002052 | 0.79 | CHRNB2 (0.35) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2536922 | 0.77 | — | — | |
| SCHEMBL18057566 | 0.76 | — | — | |
| SCHEMBL11563120 | 0.76 | — | — | |
| SCHEMBL14394185 | 0.75 | GPR84 (0.34) | GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL22042208 | 0.75 | GPR84 (0.34) | GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2118565 | 0.75 | GPR84 (0.34) | GPR84CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL3850603 | 0.75 | GPR84 (0.35) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | NAGOYA CITY UNIVERSITY (JP) | 2013-08-08 | — | — | US | disclosed |
| WO-2007005991-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN ALPHA | TRUSTEES OF TUFTS COLLEGE (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203738-A1 | USE OF COMPOUND BINDING TO MSIN3B THAT SPECIFICALLY BINDS TO NEURON RESTRICTIVE SILENCER FACTOR (NRSF) | RCOR1, MSI2, RCOR3 | GPR84 2409/4885CHRNB2 771/4885CHRNA7 1430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.