SCHEMBL4252942

SCHEMBL4252942

NNC(=O)C1C=CC=CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8247995 0.79 GPR84 (0.31) GPR84
SCHEMBL151525 0.76
SCHEMBL3850603 0.75 GPR84 (0.35) GPR84
SCHEMBL22002052 0.75 CHRNB2 (0.35) ALDH1A1
SCHEMBL14101244 0.73
SCHEMBL18598921 0.73
SCHEMBL11563120 0.71
SCHEMBL7121917 0.71
SCHEMBL17146327 0.71
SCHEMBL18057566 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108064271-A Methylotrophic Bacillus strain and the method that plant drought resistance is improved using the bacterial strain 皇家学术促进会麦吉尔大学 2018-05-22 CN disclosed
US-20170226598-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2017-08-10 US disclosed
EP-3191579-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT The Royal Institution for the Advancement of Learning / McGill University (CA) 2017-07-19 EP disclosed
WO-2016011562-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2016-01-28 WO disclosed
US-20090209474-A1 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2009-08-20 US disclosed
US-20090209474-A1 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2009-08-20 US disclosed
US-20090209474-A1 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2009-08-20 US disclosed
EP-1965778-A2 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NewThera (FR) 2008-09-10 EP disclosed
WO-2007017768-A2 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2007-02-15 WO disclosed
WO-2007017768-A2 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE NEWTHERA (FR) 2007-02-15 WO disclosed
EP-1752143-A1 Novel uses for drugs targeting glutamine synthetase NewThera (FR) 2007-02-14 EP disclosed
EP-1752143-A1 Novel uses for drugs targeting glutamine synthetase NewThera (FR) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209474-A1 NOVEL USES FOR DRUGS TARGETING GLUTAMINE SYNTHETASE GLUL, GLS2, ASNS GPR84 234/4885ALDH1A1 3778/4885
US-20170226598-A1 A BACILLUS METHYLOTROPHICUS STRAIN AND METHOD OF USING THE STRAIN TO INCREASE DROUGHT RESISTANCE IN A PLANT AMD1, AHCY, ALAD GPR84 4191/4885ALDH1A1 1038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.