Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 3/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3353214 | 0.87 | LMNA (0.44) | NTSR1PRKCILMNAKMT2AHTR6 | |
| SCHEMBL13139586 | 0.85 | NTSR1 (0.57) | NTSR1PRKCIPLAUKMT2APLG | |
| SCHEMBL2014724 | 0.82 | HTR2C (0.55) | LMNAPLAUKMT2AFAAHPLG | |
| SCHEMBL2008953 | 0.82 | HTR2A (0.55) | NTSR1LMNAPLAUKMT2AFAAH | |
| SCHEMBL2006946 | 0.82 | HTR2A (0.55) | LMNAPLAUKMT2AFAAHPLG | |
| SCHEMBL14876504 | 0.81 | NTSR1 (0.57) | NTSR1PRKCIKMT2ABRPF1CHEK1 | |
| SCHEMBL28189356 | 0.81 | NTSR1 (0.53) | NTSR1PRKCIPLAUKMT2APLG | |
| SCHEMBL1666483 | 0.79 | NTSR1 (0.52) | NTSR1PRKCILMNAATM | |
| SCHEMBL13836584 | 0.78 | NTSR1 (0.51) | NTSR1PRKCIKMT2ABRPF1CHEK1 | |
| SCHEMBL1519806 | 0.77 | KMT2A (0.71) | NTSR1LMNAPLAUKMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022321-A2 | SUBSTITUTED INDOLES AND USE THEREOF | WYETH (US) | 2007-02-22 | — | — | WO | disclosed |