Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248060 | 0.87 | NTSR1 (0.55) | LMNAKMT2ANTSR1HTR6PPARG | |
| SCHEMBL2869168 | 0.87 | KMT2A (0.60) | KMT2ANTSR1KMOKDM4EALDH1A1 | |
| SCHEMBL13139567 | 0.85 | NTSR1 (0.45) | LMNAKMT2ANTSR1KMOKDM4E | |
| SCHEMBL2006476 | 0.82 | KMO (0.61) | LMNAKMT2AKMOKDM4EALDH1A1 | |
| SCHEMBL31177216 | 0.82 | HTR2C (0.55) | LMNAKMT2AKMOKDM4EALDH1A1 | |
| SCHEMBL29958565 | 0.82 | KMO (0.61) | LMNAKMT2AKMOKDM4EALDH1A1 | |
| SCHEMBL3354646 | 0.81 | NTSR1 (0.51) | LMNAKMT2ANTSR1KDM4EALDH1A1 | |
| SCHEMBL3355234 | 0.81 | KDM4E (0.48) | LMNAKMT2ANTSR1KDM4EALDH1A1 | |
| SCHEMBL3354522 | 0.81 | GRIN2B (0.45) | NTSR1CYP2C9 | |
| SCHEMBL24414633 | 0.81 | LMNA (0.42) | LMNAKMT2AKMOKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |