Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.63 |
| ▸ | CNR2 | P34972 | 2/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MGAM | O43451 | 6/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212606 | 0.91 | CNR2 (0.61) | RORCCNR2CNR1MAPTKDM4E | |
| SCHEMBL7890904 | 0.91 | RORC (0.67) | RORCCNR2CNR1MAPTKDM4E | |
| SCHEMBL8248232 | 0.91 | CNR2 (0.65) | RORCCNR2CNR1MAPTKDM4E | |
| SCHEMBL3801324 | 0.90 | RORC (0.68) | RORCCNR2CNR1MAPTKDM4E | |
| Bicarbonate SCHEMBL7890907 | 0.89 | RORC (0.67) | RORCCNR2CNR1MAPTKDM4E | |
| SCHEMBL8207571 | 0.87 | CNR2 (0.58) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL8200351 | 0.87 | CNR2 (0.54) | RORCCNR2CNR1MAPTKDM4E | |
| SCHEMBL8206341 | 0.85 | CNR2 (0.55) | RORCCNR2CNR1MAPTKDM4E | |
| SCHEMBL8212352 | 0.85 | CNR2 (0.55) | CNR2CNR1MAPTKDM4EHSD17B10 | |
| SCHEMBL4080130 | 0.84 | RORC (0.68) | RORCMAPTKDM4EHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |