Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23712362 | 0.90 | PDK1 (0.37) | PDK1KDM4EALDH1A1PDK2PDK3 | |
| SCHEMBL7022290 | 0.87 | PDK1 (0.36) | PDK1KDM4EALDH1A1PDK2PDK3 | |
| SCHEMBL824959 | 0.87 | S1PR1 (0.41) | PDK1ALDH1A1 | |
| SCHEMBL824956 | 0.87 | S1PR1 (0.41) | PDK1ALDH1A1 | |
| SCHEMBL20298897 | 0.87 | S1PR1 (0.41) | PDK1ALDH1A1 | |
| SCHEMBL22026830 | 0.87 | S1PR1 (0.41) | PDK1ALDH1A1 | |
| SCHEMBL9801092 | 0.86 | PDK1 (0.41) | PDK1KDM4EALDH1A1PDK2PDK3 | |
| Delmopinol SCHEMBL20298306 | 0.84 | PDK1 (0.33) | PDK1KDM4EALDH1A1PDK2PDK3 | |
| Delmopinol SCHEMBL120704 | 0.84 | PDK1 (0.33) | PDK1KDM4EALDH1A1PDK2PDK3 | |
| Delmopinol SCHEMBL23705763 | 0.82 | PDK1 (0.33) | PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143463-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| US-8143463-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| US-8143463-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2011-04-21 | — | — | US | disclosed |
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2011-04-21 | — | — | US | disclosed |
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2011-04-21 | — | — | US | disclosed |
| US-7910730-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-7910730-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-7902357-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-08 | — | — | US | disclosed |
| US-7902357-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-08 | — | — | US | disclosed |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2010-09-02 | — | — | US | disclosed |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2010-09-02 | — | — | US | disclosed |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| EP-1948626-B1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1948626-B1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| EP-1948626-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | Sinclair Pharmaceuticals Limited (GB) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007057681-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057681-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | MDN1, MCOLN3, EML4 | PDK1 1553/4885KDM4E 4157/4885ALDH1A1 2327/4885 |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | MDN1, MCOLN3, EML4 | PDK1 1553/4885KDM4E 4157/4885ALDH1A1 2327/4885 |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | MDN1, MCOLN3, EML4 | PDK1 1569/4885KDM4E 4134/4885ALDH1A1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.