Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363635 | 0.88 | AVPR1A (0.64) | AVPR1AHSD11B1OXTRMCHR2 | |
| SCHEMBL8248281 | 0.77 | AVPR1A (0.81) | AVPR1AHSD11B1OXTR | |
| SCHEMBL14609348 | 0.76 | DRD3 (0.47) | AVPR1AOXTR | |
| SCHEMBL12024234 | 0.75 | DRD2 (0.47) | AVPR1AOXTR | |
| SCHEMBL14609342 | 0.74 | AVPR1A (0.43) | AVPR1AOXTR | |
| SCHEMBL14609585 | 0.74 | AVPR1A (0.57) | AVPR1AOXTR | |
| SCHEMBL12024671 | 0.72 | AVPR1A (0.76) | AVPR1AHSD11B1OXTR | |
| SCHEMBL12024705 | 0.72 | DRD2 (0.43) | AVPR1AOXTR | |
| SCHEMBL8242341 | 0.70 | AVPR1A (0.65) | AVPR1AOXTR | |
| SCHEMBL13971036 | 0.69 | HSD11B1 (0.48) | HSD11B1OXTRMCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006688-A1 | INDOL-3-CARBONYL-SPIRO-PIPERIDINE DERIVATIVES AS V1A RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-18 | — | — | WO | disclosed |