SCHEMBL824928

SCHEMBL824928

O=C(O)[C@@]1(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.51
CCNB1 P14635 1/20 0.51
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.41
TYR P14679 1/20 0.40
MAPT P10636 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
POLB P06746 1/20 0.40
PTPN1 P18031 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.40
SYNJ2 O15056 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18122709 0.88 CDK1 (0.43) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL15304599 0.88 CDK1 (0.40) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL7898994 0.86 CDK1 (0.51) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL6636531 0.85 CDK1 (0.48) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL27562514 0.84 CDK1 (0.47) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL8137909 0.83 CDK1 (0.49) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL15304634 0.81 CDK1 (0.33) CDK1CCNB1TYRMAPTCA2
SCHEMBL29015804 0.80 CDK1 (0.57) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL17779725 0.80 CDK1 (0.57) CDK1CCNB1MEN1KMT2AL3MBTL1
SCHEMBL29009296 0.80 CDK1 (0.57) CDK1CCNB1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190091650-A1 PROCESSING BIOMASS AND PETROLEUM CONTAINING MATERIALS XYLECO, INC. 2019-03-28 US disclosed
US-9968905-B2 Processing biomass XYLECO, INC. (US) 2018-05-15 US disclosed
US-9970039-B2 Processing biomass XYLECO, INC. (US) 2018-05-15 US disclosed
US-20170321233-A1 PROCESSING BIOMASS XYLECO, INC. 2017-11-09 US disclosed
US-9803222-B2 Processing biomass XYLECO, INC. (US) 2017-10-31 US disclosed
US-9745604-B2 Processing biomass XYLECO, INC. (US) 2017-08-29 US disclosed
US-9745609-B2 Processing biomass XYLECO, INC. (US) 2017-08-29 US disclosed
US-9700868-B2 Processing biomass and petroleum containing materials XYLECO, INC. (US) 2017-07-11 US disclosed
US-20170152532-A1 PROCESSING BIOMASS XYLECO, INC. 2017-06-01 US disclosed
US-20170130252-A1 PROCESSING BIOMASS XYLECO, INC. 2017-05-11 US disclosed
US-7931784-B2 Processing biomass and petroleum containing materials XYLECO, INC. (US) 2011-04-26 US disclosed
US-20110081336-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2011-04-07 US disclosed
US-20100304439-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-12-02 US disclosed
US-20100304439-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-12-02 US disclosed
US-20100304440-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-12-02 US disclosed
US-20100179315-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-07-15 US disclosed
US-20100108567-A1 PROCESSING BIOMASS AND PETROLEUM CONTAINING MATERIALS XYLECO, INC. (US) 2010-05-06 US disclosed
US-20100087687-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-04-08 US disclosed
US-20100087687-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2010-04-08 US disclosed
US-20090286295-A1 PROCESSING BIOMASS XYLECO, INC. (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100304440-A1 PROCESSING BIOMASS GYS2, GYS1, MGAM CDK1 4153/4885CCNB1 2046/4885MEN1 1814/4885
US-20100087687-A1 PROCESSING BIOMASS GYS2, GYS1, MGAM CDK1 4153/4885CCNB1 2046/4885MEN1 1814/4885
US-20100179315-A1 PROCESSING BIOMASS GYS2, GYS1, MGAM CDK1 4153/4885CCNB1 2046/4885MEN1 1814/4885
US-20170321233-A1 PROCESSING BIOMASS FIP1L1, MANBA, BCAT2 CDK1 2948/4885CCNB1 1110/4885MEN1 1605/4885
US-20110081336-A1 PROCESSING BIOMASS FIP1L1, MANBA, BCAT2 CDK1 2948/4885CCNB1 1110/4885MEN1 1605/4885
US-20100108567-A1 PROCESSING BIOMASS AND PETROLEUM CONTAINING MATERIALS GYS2, GYS1, AGL CDK1 3815/4885CCNB1 1607/4885MEN1 1467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.