SCHEMBL824960

SCHEMBL824960

Nc1cccc2ccoc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CYP3A4 P08684 4/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KEAP1 Q14145 1/20 0.41
TDP1 Q9NUW8 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP3 P42574 1/20 0.38
KMT2A Q03164 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6636244 0.98 NPC1 (0.44) NPC1RAB9ACYP3A4ALDH1A1HPGD
SCHEMBL3798990 0.76 CYP1A2 (0.41) NPC1RAB9ACYP3A4TDP1SMN1; SMN2
SCHEMBL5424464 0.71 MEN1 (0.38) NPC1RAB9ACYP3A4TDP1SMN1; SMN2
SCHEMBL2007380 0.71 MEN1 (0.38) NPC1RAB9ACYP3A4TDP1SMN1; SMN2
SCHEMBL6261842 0.71 ADORA2A (0.42) NPC1RAB9ACYP3A4ALDH1A1HPGD
SCHEMBL104411 0.71 MEN1 (0.38) NPC1RAB9ACYP3A4TDP1SMN1; SMN2
SCHEMBL276858 0.71 MEN1 (0.38) NPC1RAB9ACYP3A4TDP1SMN1; SMN2
SCHEMBL288995 0.71 MEN1 (0.38) NPC1RAB9ACYP3A4TDP1SMN1; SMN2
SCHEMBL276859 0.71 ADORA2A (0.42) NPC1RAB9ACYP3A4ALDH1A1HPGD
SCHEMBL2589546 0.71 MEN1 (0.38) NPC1RAB9ACYP3A4TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400591-A1 COMPOUNDS TARGETING MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-12-05 US claimed
CN-118507514-B Preparation method of longitudinal beta gallium oxide NPN transistor 深圳市港祥辉电子有限公司 2024-11-01 CN claimed
CN-118507514-A Preparation method of longitudinal beta gallium oxide NPN transistor 深圳市港祥辉电子有限公司 2024-08-16 CN claimed
WO-2026090348-A1 THE USE OF SON OF SEVENLESS (SOS) INHIBITOR COMPOUNDS SUCH AS 7-SUBSTITUTED BENZOFURANS TO TREAT CANCER Mirati Therapeutics, Inc. (US) 2026-04-30 WO disclosed
US-20250214948-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2025-07-03 US disclosed
US-20240400591-A1 COMPOUNDS TARGETING MUTANT OF P53 JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2024-12-05 US disclosed
CN-118507514-B Preparation method of longitudinal beta gallium oxide NPN transistor 深圳市港祥辉电子有限公司 2024-11-01 CN disclosed
CN-118507514-A Preparation method of longitudinal beta gallium oxide NPN transistor 深圳市港祥辉电子有限公司 2024-08-16 CN disclosed
US-20240246908-A1 TEAD INHIBITORS ORION CORPORATION (FI) 2024-07-25 US disclosed
EP-4395520-A2 LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
EP-3862360-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-03 EP disclosed
EP-0490772-A1 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1992-06-17 EP disclosed
US-5068359-A Fungicides of benzothiophene and benzofuran compounds CIBA-GEIGY CORPORATION (US) 1991-11-26 US disclosed
EP-0079683-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-06 EP disclosed
US-4647677-A Process for preparing 2,3-dihydro-7-aminobenzofurans MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-03-03 US disclosed
US-4514211-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US disclosed
US-4398028-A HYPOTENSIVE, MUSCLE RELAXANTS SANDOZ LTD. (CH) 1983-08-09 US disclosed
EP-0079683-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-25 EP disclosed
US-4297490-A HYPOTENSIVE AND ANTISPASMODIC AGENTS SANDOZ LTD. (CH) 1981-10-27 US disclosed
US-4077953-A Tri-dentate metal complex azo pigments CIBA-GEIGY CORPORATION (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214948-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS NTRK2, BDNF, NGF NPC1 1016/4885RAB9A 3039/4885CYP3A4 4531/4885
US-20240246908-A1 TEAD INHIBITORS TEAD3, TEAD1, TEAD2 NPC1 783/4885RAB9A 112/4885CYP3A4 1748/4885
US-20240400591-A1 COMPOUNDS TARGETING MUTANT OF P53 TP53, TP53BP1, MDM2 NPC1 1540/4885RAB9A 2731/4885CYP3A4 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.