Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.35 |
| ▸ | CASP5 | P51878 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP9 | P55211 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8279959 | 0.93 | CASP1 (0.36) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL8246714 | 0.90 | ELANE (0.37) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL16313124 | 0.90 | CMA1 (0.40) | CMA1NR1I2 | |
| SCHEMBL8240611 | 0.89 | DPP4 (0.38) | CMA1OPRM1 | |
| SCHEMBL8250731 | 0.88 | ELANE (0.36) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL8252293 | 0.87 | ELANE (0.36) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8247468 | 0.86 | ELANE (0.43) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL12601266 | 0.86 | ELANE (0.46) | CASP1CASP4CASP5CASP7CASP9 | |
| SCHEMBL8254539 | 0.84 | CTSB (0.44) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12143755 | 0.83 | NR1I2 (0.35) | CASP1CASP4CASP5CASP7CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130686-A2 | HCV PROTEASE INHIBITORS IN COMBINATION WITH FOOD | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006130607-A2 | CONTROLLED-RELEASE FORMULATION USEFUL FOR TREATING DISORDERS ASSOCIATED WITH HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |