Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 11/20 | 0.44 |
| ▸ | CTSL | P07711 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.41 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280579 | 0.90 | CTSB (0.42) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL8245795 | 0.90 | CTSB (0.39) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL13225080 | 0.84 | CTSB (0.39) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL8278558 | 0.84 | ABCG2 (0.40) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL13225074 | 0.84 | CTSB (0.39) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL8249903 | 0.84 | CASP1 (0.35) | CTSBCTSLCTSKCTSVELANE | |
| SCHEMBL10276788 | 0.84 | CTSB (0.41) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL13225081 | 0.84 | CTSB (0.38) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL13225078 | 0.84 | CTSB (0.38) | CTSBCTSLCTSKABCG2CTSV | |
| SCHEMBL10276630 | 0.83 | ABCG2 (0.38) | CTSBCTSLCTSKABCG2CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130686-A2 | HCV PROTEASE INHIBITORS IN COMBINATION WITH FOOD | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006130628-A2 | COMBINATION OF HCV PROTEASE INHIBITORS WITH A SURFACTANT | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |