Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283845 | 0.85 | ALDH1A1 (0.62) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL4747138 | 0.84 | CHRM2 (0.63) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| Potassium Ion SCHEMBL1473743 | 0.80 | TSHR (0.48) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL14220155 | 0.80 | MEN1 (0.56) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL1474021 | 0.79 | ALDH1A1 (0.65) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL9445313 | 0.78 | HIF1A (0.46) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL4743411 | 0.76 | ALDH1A1 (0.51) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL19501378 | 0.76 | GAA (0.52) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL19513572 | 0.76 | TSHR (0.50) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 | |
| SCHEMBL8362958 | 0.76 | LMNA (0.68) | CHRM2ADRA2ADRD1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006714-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |