Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744577 | 0.86 | RAB9A (0.56) | HPGDMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8283845 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL4747138 | 0.81 | CHRM2 (0.63) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14220155 | 0.79 | MEN1 (0.56) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL1474021 | 0.78 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL838271 | 0.77 | KMT2A (0.48) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| Potassium Ion SCHEMBL1473743 | 0.77 | TSHR (0.48) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL8250244 | 0.76 | CHRM2 (0.48) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL23754981 | 0.74 | LSS (0.56) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| Trimethylammonium SCHEMBL993437 | 0.74 | CYP2C19 (0.69) | ALDH1A1HPGDMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |