Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.61 |
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917212 | 0.89 | TTR (0.68) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL917211 | 0.89 | TTR (0.68) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL8360408 | 0.87 | GALR3 (0.48) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL12852971 | 0.86 | GALR3 (0.60) | TTRGALR3HTR4MAPTKMT2A | |
| SCHEMBL8273654 | 0.84 | GALR3 (0.63) | TTRGALR3HTR4 | |
| SCHEMBL8250410 | 0.83 | GALR3 (0.48) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL5356411 | 0.81 | GALR3 (0.56) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL5356416 | 0.81 | GALR3 (0.56) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL8360397 | 0.81 | GALR3 (0.50) | TTRGALR3HTR4MAPTNPSR1 | |
| SCHEMBL5357195 | 0.81 | GALR3 (0.53) | TTRGALR3HTR4MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082615-A1 | 3-Imino-2-indolones for the treatement of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082615-A1 | 3-Imino-2-indolones for the treatement of depression and/or anxiety | GALR3, GALR2, GALR1 | TTR 4705/4885GALR3 1/4885HTR4 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.