Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917249 | 0.89 | GALR3 (0.58) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL917246 | 0.89 | GALR3 (0.58) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL8250355 | 0.87 | TTR (0.61) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL8253729 | 0.86 | GALR3 (0.57) | GALR3HTR4ESR1ESR2TTR | |
| SCHEMBL8273654 | 0.84 | GALR3 (0.63) | GALR3HTR4TTR | |
| SCHEMBL5356416 | 0.81 | GALR3 (0.56) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL5356411 | 0.81 | GALR3 (0.56) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL8360397 | 0.81 | GALR3 (0.50) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL5357195 | 0.81 | GALR3 (0.53) | GALR3HTR4TTRMAPTNPSR1 | |
| SCHEMBL5357199 | 0.81 | GALR3 (0.53) | GALR3HTR4TTRMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014854-A1 | 3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |