Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GPR6 | P46095 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240451 | 0.82 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL8239707 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRGPR6MAPTGAA | |
| SCHEMBL8247932 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EL3MBTL1TSHRMAPT | |
| SCHEMBL4721325 | 0.77 | HSD11B1 (0.59) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL4524859 | 0.76 | NPY5R (0.52) | ALDH1A1SMN1; SMN2KDM4ETSHRNPY5R | |
| SCHEMBL4721446 | 0.74 | GAA (0.59) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL4766135 | 0.72 | USP2 (0.57) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL8247070 | 0.72 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL4513123 | 0.71 | NPY5R (0.48) | ALDH1A1SMN1; SMN2NPY5RLMNAMAPT | |
| SCHEMBL14355835 | 0.71 | TSHR (0.52) | ALDH1A1SMN1; SMN2TSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009635-A1 | PHENYL SUBSTITUTED PIPERAZINE-DERIVATIVES AS INHIBITORS OF PLAMINOGENIC ACTIVATOR INHIBITORS-I (PAI-I) | BAYER HEALTHCARE AG (DE) | 2007-01-25 | — | — | WO | disclosed |