Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721446 | 0.91 | GAA (0.59) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL4721325 | 0.84 | HSD11B1 (0.59) | ALDH1A1KDM4ESMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL8247932 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL4722869 | 0.82 | AKR1C3 (0.58) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4718989 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL8250573 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4719103 | 0.81 | ABL1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL8247070 | 0.79 | SMN1; SMN2 (0.72) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL23064276 | 0.78 | GAA (0.67) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL9565871 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009635-A1 | PHENYL SUBSTITUTED PIPERAZINE-DERIVATIVES AS INHIBITORS OF PLAMINOGENIC ACTIVATOR INHIBITORS-I (PAI-I) | BAYER HEALTHCARE AG (DE) | 2007-01-25 | — | — | WO | disclosed |